For some time now I've been using iSilo a lot, with lots of sites (medical, of course ) on my hdd and pda (tungsten t3), and I've been gathering so much info in pdb format that in my oppinion would be a great thing if there were a desktop search plugin for pdb files.
The search function in isilo is ok, but desktop indexing would be great. I saw that google makes the sdk free, and that there are already lot's of plug-ins that give away their source for free - I am not to much of a programer and nevertheless the isilo file format is not public - but maybe the authors of this absolutely great program would care for such an extension to the isilo family.
As benefits I would mention the increased google advertisement
All the best!